University of Texas

The Aldrich Lab

The University of Texas at Austin | The School of Biological Sciences | The Section of Neurobiology | The Center for Learning and Memory

Current Members


Xixi Chen

"I joined the Aldrich lab in the fall of 2006, with a background in cellular neurophysiology and seeking training in molecular biophysics. I now work on the biophysics of small-conductance, calcium-activated potassium (SK) channels."

Jennifer Greeson

"I joined the Aldrich lab in April of 2008 after completing my graduate studies at Rice University in Bioengineering. Combining my love of all things fluorescent with an interest in ion channel gating mechanisms, I am currently working with Tom investigating the activation of SK channels using lanthanide ions as spectroscopic probes."

Brent Halling

"I formally met Dr. Aldrich in an alligator swamp in southeast Texas during a departmental retreat while I was a graduate student at the Baylor College of Medicine. We found common interests in the regulation of ion channels by calcium dependent modulators. I recently joined his lab in November 2007 with the intent to elucidate mechanisms involved in channel modulation by calcium sensors."


Tom Middendorf

"After completing my doctoral studies on electron transfer in photosynthetic reaction centers at Stanford University in 1991, I literally moved across the street to start postdoctoral work on ion channels in the Aldrich and Baylor labs (then located at the Stanford School of Medicine).  The common thread in these seemingly unrelated areas is my interest in how charges move within and across biological membranes.  My work in the Aldrich lab has combined spectroscopic and electrophysiological techniques to study cyclic nucleotide-activated channels and calcium-activated potassium channels.  Since moving with the lab to the University of Texas at Austin, I have been using lanthanide ions as spectroscopic probes to investigate the activation of SK channels by calcium, and have greatly increased my intake of Mexican food."

Luisa Scott

"I received my PhD from the University of Rochester in 2003 after exhibiting extreme proficiency at the art of bird-catching. I moved to Austin and changed to ground-dwelling mammals for postdoctoral work studying cellular neurophysiology in the auditory brainstem. To continue and expand on this work/species list, I joined the Aldrich lab in 2008. I am exploring how protein-protein interactions tailor the biophysical properties of SK channels to the specific functional role these channels play in several auditory brainstem nuclei."

Graduate Students

Keegan Hines

"I completed my undergraduate degree in Physics at Washington and Lee University and am a graduate student in the Institute for Neuroscience. I use electrophysiology, fluorescence spectroscopy, and quantitative modeling to understand conformational dynamics in proteins."




Curious about Dr. Aldrich's former lab members? Please click here to view a list of lab alumni.